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Inter-individual Variability in the Pre-clinical Drug Cardiotoxic Safety Assessment—Analysis of the Age–Cardiomyocytes Electric Capacitance Dependence

Electrical phenomena located within the plasma membrane of the mammalian cardiac cells are connected with the cells’ main physiological functions—signals processing and contractility. They were extensively studied and described mathematically in so-called Hodgkin–Huxley paradigm. One of the physiolo...

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Autors principals: Polak, Sebastian, Fijorek, Kamil
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349867/
https://ncbi.nlm.nih.gov/pubmed/22411323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-012-9357-8
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