Promotion of a Functional B Cell Germinal Center Response after Leishmania Species Co-Infection Is Associated with Lesion Resolution

Co-infection of C3HeB/FeJ (C3H) mice with both Leishmania major and Leishmania amazonensis leads to a healed footpad lesion, whereas co-infection of C57BL/6 (B6) mice leads to non-healing lesions. This inability to heal corresponds to a deficiency in B cell stimulation of the macrophage-mediated kil...

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Main Authors: Gibson-Corley, Katherine N., Boggiatto, Paola M., Bockenstedt, Marie M., Petersen, Christine A., Waldschmidt, Thomas J., Jones, Douglas E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2012
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349825/
https://ncbi.nlm.nih.gov/pubmed/22429963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.01.012
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