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Regulation of suppressive function of myeloid-derived suppressor cells by CD4(+) T cells MDSC and CD4(+) T cells

Myeloid derived Suppressor Cells play a critical role in T cell suppression in cancer. Here, we discuss the mechanisms of how MDSC suppress CD4(+) or CD8(+) T cells in an antigen dependent or non-dependent manner.

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Détails bibliographiques
Auteurs principaux: Nagaraj, Srinivas, Gabrilovich, Dmitry I.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349790/
https://ncbi.nlm.nih.gov/pubmed/22313876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2012.01.010
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