Histone H1 Depletion Impairs Embryonic Stem Cell Differentiation

Pluripotent embryonic stem cells (ESCs) are known to possess a relatively open chromatin structure; yet, despite efforts to characterize the chromatin signatures of ESCs, the role of chromatin compaction in stem cell fate and function remains elusive. Linker histone H1 is important for higher-order...

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Autori principali: Zhang, Yunzhe, Cooke, Marissa, Panjwani, Shiraj, Cao, Kaixiang, Krauth, Beth, Ho, Po-Yi, Medrzycki, Magdalena, Berhe, Dawit T., Pan, Chenyi, McDevitt, Todd C., Fan, Yuhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349736/
https://ncbi.nlm.nih.gov/pubmed/22589736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002691
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