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Increased nicotinic receptor desensitization in hypoglossal motor neurons following chronic developmental nicotine exposure

Neuronal nicotinic acetylcholine receptors (nAChRs) are expressed on hypoglossal motor neurons (XII MNs) that innervate muscles of the tongue. Activation of XII MN nAChRs evokes depolarizing currents, which are important for regulating the size and stiffness of the upper airway. Although data show t...

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Bibliografiske detaljer
Main Authors: Pilarski, Jason Q., Wakefield, Hilary E., Fuglevand, Andrew J., Levine, Richard B., Fregosi, Ralph F.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349681/
https://ncbi.nlm.nih.gov/pubmed/22013232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00623.2011
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