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Factors Determining Sensitivity and Resistance of Tumor Cells to Arsenic Trioxide

Previously, arsenic trioxide showed impressive regression rates of acute promyelocytic leukemia. Here, we investigated molecular determinants of sensitivity and resistance of cell lines of different tumor types towards arsenic trioxide. Arsenic trioxide was the most cytotoxic compound among 8 arseni...

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Detalhes bibliográficos
Main Authors: Sertel, Serkan, Tome, Margaret, Briehl, Margaret M., Bauer, Judith, Hock, Kai, Plinkert, Peter K., Efferth, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349672/
https://ncbi.nlm.nih.gov/pubmed/22590507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035584
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