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Recombination mediates production of an extrachromosomal circular DNA containing a transposon-like human element, THE-1.

An abundant class of HeLa extrachromosomal circular DNA containing the transposon-like element, THE-1, is shown to arise via site specific recombination. The chromosomal locus from which these circles are derived, however, is single-copy. Northern blot analysis detects homology to two polyadenylated...

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Main Authors: Misra, R, Matera, A G, Schmid, C W, Rush, M G
Format: Artigo
Jezik:Inglês
Izdano: 1989
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC334967/
https://ncbi.nlm.nih.gov/pubmed/2478961
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