Diacylglycerol Kinase β Knockout Mice Exhibit Attention-Deficit Behavior and an Abnormal Response on Methylphenidate-Induced Hyperactivity

BACKGROUND: Diacylglycerol kinase (DGK) is an enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. DGKβ is one of the subtypes of the DGK family and regulates many intracellular signaling pathways in the central nervous system. Previously, we demonstrated that DGKβ knockout (KO) m...

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Autores principales: Ishisaka, Mitsue, Kakefuda, Kenichi, Oyagi, Atsushi, Ono, Yoko, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Kitaichi, Kiyoyuki, Hara, Hideaki
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349656/
https://ncbi.nlm.nih.gov/pubmed/22590645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037058
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