Phosphoroselenoate oligodeoxynucleotides: synthesis, physico-chemical characterization, anti-sense inhibitory properties and anti-HIV activity.

Oligodeoxynucleotides with a phosphorus atom in which one of the non-bridging oxygen atoms is substituted by selenium were prepared and investigated with respect to their antisense properties. A general synthesis of phosphoroselenoate analogs of oligonucleotides is described using potassium selenocy...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Mori, K, Boiziau, C, Cazenave, C, Matsukura, M, Subasinghe, C, Cohen, J S, Broder, S, Toulmé, J J, Stein, C A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1989
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334959/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2682524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.20.8207
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