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Chondrogenic differentiation of human subchondral progenitor cells is affected by synovial fluid from donors with osteoarthritis or rheumatoid arthritis

BACKGROUND: Microfracture is a first-line treatment option for cartilage repair. In microfracture, subchondral mesenchymal cortico-spongious progenitor cells (CSP) enter the defect and form cartilage repair tissue. The aim of our study was to investigate the effects of joint disease conditions on th...

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Main Authors: Krüger, Jan Philipp, Endres, Michaela, Neumann, Katja, Stuhlmüller, Bruno, Morawietz, Lars, Häupl, Thomas, Kaps, Christian
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349532/
https://ncbi.nlm.nih.gov/pubmed/22414301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-799X-7-10
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