Surfactant protein B inhibits secretory phospholipase A(2) hydrolysis of surfactant phospholipids

Hydrolysis of surfactant phospholipids (PL) by secretory phospholipases A(2) (sPLA(2)) contributes to surfactant damage in inflammatory airway diseases such as acute lung injury/acute respiratory distress syndrome. We and others have reported that each sPLA(2) exhibits specificity in hydrolyzing dif...

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Hlavní autoři: Hite, R. Duncan, Grier, Bonnie L., Waite, B. Moseley, Veldhuizen, Ruud A., Possmayer, Fred, Yao, Li-Juan, Seeds, Michael C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349360/
https://ncbi.nlm.nih.gov/pubmed/22037357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00054.2011
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