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Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells

OBJECTIVES: Panaxadiol (PD) is a purified sapogenin of ginseng saponins that exhibits anticancer activity. Irinotecan (IRN) is a second line anticancer drug, but clinical treatment with IRN is limited due to side effects. In this study, we investigated the possible synergistic anticancer effects of...

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Detalhes bibliográficos
Main Authors: Du, Guang-Jian, Wang, Chong-Zhi, Zhang, Zhi-Yu, Wen, Xiao-Dong, Somogyi, Jacqueline, Calway, Tyler, He, Tong-Chuan, Du, Wei, Yuan, Chun-Su
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349342/
https://ncbi.nlm.nih.gov/pubmed/22471369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2042-7158.2012.01463.x
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