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Developing genetically engineered mouse models to study tumor suppression
Since the late 1980s, the tools to generate mice with deletions of tumor suppressors have made it possible to study such deletions in the context of a whole animal. Deletion of some tumor suppressors results in viable mice while deletion of others yield embryo lethal phenotypes cementing the concept...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349200/ https://ncbi.nlm.nih.gov/pubmed/22582146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470942390.mo110159 |
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