Disulfiram Metabolite S-Methyl-N, N-Diethylthiocarbamate Quantitation in Human Plasma with Reverse Phase Ultra Performance Liquid Chromatography and Mass Spectrometry

Disulfiram has been used extensively for alcohol abuse and may have a role in treatment for cocaine addiction. Recent data suggest that disulfiram may also reactivate latent HIV in reservoirs. Disulfiram has complex pharmacokinetics with rapid metabolism to active metabolites, including S-Methyl-N,...

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Autori principali: Hochreiter, Jill, McCance-Katz, Elinore F., Lapham, Jill, Ma, Qing, Morse, Gene D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348964/
https://ncbi.nlm.nih.gov/pubmed/22534656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2012.03.035
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