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Ubiquitin-Specific Protease 25 Functions in Endoplasmic Reticulum-Associated Degradation
Endoplasmic Reticulum (ER)-associated degradation (ERAD) discards abnormal proteins synthesized in the ER. Through coordinated actions of ERAD components, misfolded/anomalous proteins are recognized, ubiquitinated, extracted from the ER and ultimately delivered to the proteasome for degradation. It...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348923/ https://ncbi.nlm.nih.gov/pubmed/22590560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036542 |
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