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Selective Activation of p120(ctn)-Kaiso Signaling to Unlock Contact Inhibition of ARPE-19 Cells without Epithelial-Mesenchymal Transition

Contact-inhibition ubiquitously exists in non-transformed cells and explains the poor regenerative capacity of in vivo human retinal pigment epithelial cells (RPE) during aging, injury and diseases. RPE injury or degeneration may unlock mitotic block mediated by contact inhibition but may also promo...

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Detalhes bibliográficos
Main Authors: Chen, Hung-Chi, Zhu, Ying-Ting, Chen, Szu-Yu, Tseng, Scheffer C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348893/
https://ncbi.nlm.nih.gov/pubmed/22590627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036864
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