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Oxidation of Low-Density Lipoprotein by Iron at Lysosomal pH: Implications for Atherosclerosis

[Image: see text] Low-density lipoprotein (LDL) has recently been shown to be oxidized by iron within the lysosomes of macrophages, and this is a novel potential mechanism for LDL oxidation in atherosclerosis. Our aim was to characterize the chemical and physical changes induced in LDL by iron at ly...

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Autori principali: Satchell, Leanne, Leake, David S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2012
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348679/
https://ncbi.nlm.nih.gov/pubmed/22493939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2017975
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