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Penalized logistic regression for high-dimensional DNA methylation data with case-control studies
Motivation: DNA methylation is a molecular modification of DNA that plays crucial roles in regulation of gene expression. Particularly, CpG rich regions are frequently hypermethylated in cancer tissues, but not methylated in normal tissues. However, there are not many methodological literatures of c...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348559/ https://ncbi.nlm.nih.gov/pubmed/22467913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts145 |
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