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Penalized logistic regression for high-dimensional DNA methylation data with case-control studies

Motivation: DNA methylation is a molecular modification of DNA that plays crucial roles in regulation of gene expression. Particularly, CpG rich regions are frequently hypermethylated in cancer tissues, but not methylated in normal tissues. However, there are not many methodological literatures of c...

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Detalhes bibliográficos
Main Authors: Sun, Hokeun, Wang, Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348559/
https://ncbi.nlm.nih.gov/pubmed/22467913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts145
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