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Penalized logistic regression for high-dimensional DNA methylation data with case-control studies

Motivation: DNA methylation is a molecular modification of DNA that plays crucial roles in regulation of gene expression. Particularly, CpG rich regions are frequently hypermethylated in cancer tissues, but not methylated in normal tissues. However, there are not many methodological literatures of c...

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Autors principals: Sun, Hokeun, Wang, Shuang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348559/
https://ncbi.nlm.nih.gov/pubmed/22467913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts145
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