Markers of Cholesterol Metabolism in the Brain Show Stronger Associations with Cerebrovascular Disease than Alzheimer’s Disease

Cholesterol metabolism is believed to play a role in the development of Alzheimer’s disease (AD). Oxysterol metabolites of cholesterol, 24S-hydroxycholesterol (24-OHC, a brain-derived oxysterol) and 27-hydroxycholesterol (27-OHC, a peripherally derived oxysterol) cross the blood brain barrier and ha...

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Main Authors: Hughes, Timothy M., Kuller, Lewis K., Lopez, Oscar L., Becker, James T., Evans, Rhobert W., Sutton-Tyrrell, Kim, Rosano, Caterina
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348402/
https://ncbi.nlm.nih.gov/pubmed/22377780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-111460
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