Mesenchymal Stem Cell-Induced Immunoregulation Involves Fas Ligand/Fas-Mediated T Cell Apoptosis

Systemic infusion of bone marrow mesenchymal stem cells (BMMSCs) shows therapeutic benefit for a variety of autoimmune diseases, but the underlying mechanisms are poorly understood. Here we show that in mice systemic infusion of BMMSCs induced transient T-cell apoptosis via the Fas ligand (FasL)-dep...

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Main Authors: Akiyama, Kentaro, Chen, Chider, Wang, DanDan, Xu, Xingtian, Qu, Cunye, Yamaza, Takayoshi, Cai, Tao, Chen, WanJun, Sun, Lingyun, Shi, Songtao
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348385/
https://ncbi.nlm.nih.gov/pubmed/22542159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.03.007
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