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Live free or die: Stretch-induced apoptosis occurs when adaptive reorientation of annulus fibrosus cells is restricted

High matrix strains in the intervertebral disc occur during physiological motions and are amplified around structural defects in the annulus fibrosus (AF). It remains unknown if large matrix strains in the human AF result in localized cell death. This study investigated strain amplitudes and substra...

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Bibliografiske detaljer
Main Authors: Abbott, Rosalyn D, Howe, Alan K, Langevin, Helene M, Iatridis, James C
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348381/
https://ncbi.nlm.nih.gov/pubmed/22516752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.04.018
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