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Immunoglobulin kappa light chain gene promoter and enhancer are not responsible for B-cell restricted gene rearrangement.

We have produced transgenic mice which synthesize chimeric mouse-rabbit immunoglobulin (Ig) kappa light chains following in vivo recombination of an injected unrearranged kappa gene. The exogenous gene construct contained a mouse germ-line kappa variable (V kappa) gene segment, the mouse germ-line j...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Goodhardt, M, Babinet, C, Lutfalla, G, Kallenbach, S, Cavelier, P, Rougeon, F
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1989
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2508061/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.18.7403
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