Expansion of somatically reverted memory CD8(+) T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus

Patients with the primary immunodeficiency X-linked lymphoproliferative disease (XLP), which is caused by mutations in SH2D1A, are highly susceptible to Epstein-Barr virus (EBV) infection. Nonetheless, some XLP patients demonstrate less severe clinical manifestations after primary infection. SH2D1A...

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Main Authors: Palendira, Umaimainthan, Low, Carol, Bell, Andrew I., Ma, Cindy S., Abbott, Rachel J.M., Phan, Tri Giang, Riminton, D. Sean, Choo, Sharon, Smart, Joanne M., Lougaris, Vassilios, Giliani, Silvia, Buckley, Rebecca H., Grimbacher, Bodo, Alvaro, Frank, Klion, Amy D., Nichols, Kim E., Adelstein, Stephen, Rickinson, Alan B., Tangye, Stuart G.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Brief Definitive Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348103/
https://ncbi.nlm.nih.gov/pubmed/22493517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112391
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