Resident CD141 (BDCA3)(+) dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

Human skin immune homeostasis, and its regulation by specialized subsets of tissue-residing immune sentinels, is poorly understood. In this study, we identify an immunoregulatory tissue-resident dendritic cell (DC) in the dermis of human skin that is characterized by surface expression of CD141, CD1...

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Detalhes bibliográficos
Main Authors: Chu, Chung-Ching, Ali, Niwa, Karagiannis, Panagiotis, Di Meglio, Paola, Skowera, Ania, Napolitano, Luca, Barinaga, Guillermo, Grys, Katarzyna, Sharif-Paghaleh, Ehsan, Karagiannis, Sophia N., Peakman, Mark, Lombardi, Giovanna, Nestle, Frank O.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348099/
https://ncbi.nlm.nih.gov/pubmed/22547651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112583
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