Loss of PPARγ expression by fibroblasts enhances dermal wound closure

BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)γ may be a key regulator of connective tissue deposition and remodeling in vivo. PPARγ expression is reduced in dermal fibroblasts isolated from fibrotic areas of scleroderma patients; PPARγ agonists suppress the persistent fibrotic phenot...

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Main Authors: Sha, Wei, Thompson, Katherine, South, Jennifer, Baron, Murray, Leask, Andrew
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348009/
https://ncbi.nlm.nih.gov/pubmed/22502865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-5-5
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