Targeting of prion-infected lymphoid cells to the central nervous system accelerates prion infection

BACKGROUND: Prions, composed of a misfolded protein designated PrP(Sc), are infectious agents causing fatal neurodegenerative diseases. We have shown previously that, following induction of experimental autoimmune encephalomyelitis, prion-infected mice succumb to disease significantly earlier than c...

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Main Authors: Friedman-Levi, Yael, Hoftberger, Romana, Budka, Herbert, Mayer-Sonnenfeld, Tehila, Abramsky, Oded, Ovadia, Haim, Gabizon, Ruth
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347999/
https://ncbi.nlm.nih.gov/pubmed/22436404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-58
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