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Bifunctional oligonucleotide probes synthesized using a novel CPG support are able to detect single base pair mutations.
A novel multifunctional controlled pore glass, MF-CPG (Fig. 1), has been synthesized and used to incorporate 3' terminal primary aliphatic amines into synthetic oligonucleotides. MF-CPG consists of a unique succinic acid linking arm which possesses both a masked primary amine for label attachme...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1989
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| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2677994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.18.7187 |
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