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A new and versatile reagent for incorporating multiple primary aliphatic amines into synthetic oligonucleotides.

A novel and versatile phosphoramidite, N-Fmoc-O1-DMT-O2-cyanoethoxydiisopropylamino-phosphinyl-3-am ino-1,2-propanediol (1, Fig. 1), has been synthesized and used to incorporate primary aliphatic amines into synthetic oligonucleotides. Its convenient preparation and use in solid phase oligonucleotid...

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Bibliografiske detaljer
Main Authors: Nelson, P S, Sherman-Gold, R, Leon, R
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC334797/
https://ncbi.nlm.nih.gov/pubmed/2798089
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