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Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing
Oncolytic herpes simplex virus type 1 (HSV-1) vectors are promising therapeutic agents for cancer. Their efficacy depends on the extent of both intratumoral viral replication and induction of a host antitumor immune response. To enhance these properties while employing ample safeguards, two conditio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33479/ https://ncbi.nlm.nih.gov/pubmed/11353831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101136398 |
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