Codependency of H2B monoubiquitination and nucleosome reassembly on Chd1

Monoubiquitination of histone H2B on Lys 123 (H2BK123ub) is a transient histone modification considered to be essential for establishing H3K4 and H3K79 trimethylation by Set1/COMPASS and Dot1, respectively. Here, we identified Chd1 as a factor that is required for the maintenance of high levels of H...

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Autori principali: Lee, Jung-Shin, Garrett, Alexander S., Yen, Kuangyu, Takahashi, Yoh-Hei, Hu, Deqing, Jackson, Jessica, Seidel, Christopher, Pugh, B. Franklin, Shilatifard, Ali
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2012
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347789/
https://ncbi.nlm.nih.gov/pubmed/22549955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.186841.112
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