HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature

HOT (highly occupied target) regions bound by many transcription factors are considered to be one of the most intriguing findings of the recent modENCODE reports, yet their functions have remained unclear. We tested 108 Drosophila melanogaster HOT regions in transgenic embryos with site-specifically...

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Bibliographic Details
Main Authors: Kvon, Evgeny Z., Stampfel, Gerald, Yáñez-Cuna, J. Omar, Dickson, Barry J., Stark, Alexander
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2012
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347788/
https://ncbi.nlm.nih.gov/pubmed/22499593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.188052.112
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