Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia

BACKGROUND: Protein phosphatase 2A is a novel potential therapeutic target in several types of chronic and acute leukemia, and its inhibition is a common event in acute myeloid leukemia. Upregulation of SET is essential to inhibit protein phosphatase 2A in chronic myeloid leukemia, but its importanc...

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Autors principals: Cristóbal, Ion, Garcia-Orti, Laura, Cirauqui, Cristina, Cortes-Lavaud, Xabier, García-Sánchez, María A., Calasanz, María J., Odero, María D.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2012
Matèries:
Original Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347675/
https://ncbi.nlm.nih.gov/pubmed/22133779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.050542
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