BCR and TLR signaling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas

The genetics and pathogenesis of splenic marginal zone lymphoma are poorly understood. The lymphoma lacks chromosome translocation, and approximately 30% of cases are featured by 7q deletion, but the gene targeted by the deletion is unknown. A recent study showed inactivation of A20, a “global” NF-κ...

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Bibliographische Detailangaben
Hauptverfasser: Yan, Qingguo, Huang, Yuanxue, Watkins, A. James, Kocialkowski, Sylvia, Zeng, Naiyan, Hamoudi, Rifat A., Isaacson, Peter G., de Leval, Laurence, Wotherspoon, Andrew, Du, Ming-Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2012
Schlagworte:
Original Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347666/
https://ncbi.nlm.nih.gov/pubmed/22102703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.054080
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