New Test System for Serine/Threonine Protein Kinase Inhibitors Screening: E. coli APHVIII/Pk25 design.

An efficient test system for serine/threonine protein kinase inhibitors screening has been developed based on theE. coliprotein system APHVIII/Pk25. Phosphorylation of aminoglycoside phosphotransferase VIII (APHVIII) by protein kinases enhances resistance of the bacterial cell to aminoglycoside anti...

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Autores principales: Bekker, O.B., Alekseeva, M.G., Osolodkin, D.I., Palyulin, V.A., Elizarov, S.M., Zefirov, N.S., Danilenko, V.N.
Formato: Artigo
Lenguaje:Inglês
Publicado: A.I. Gordeyev 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347566/
https://ncbi.nlm.nih.gov/pubmed/22649658
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