New 5-Modified Pyrimidine Nucleoside Inhibitors of Mycobacterial Growth

The WHO has declared tuberculosis (TB) a global health emergency. Therefore, there is an urgent need to discover and develop new anti–TB drugs. Here we report on a new category of 5–substituted pyrimidine nucleosides as potent inhibitors of Myco–bacterium tuberculosis growth in vitro. A series of 2ʹ...

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Hauptverfasser: Alexandrova, L.A., Shmalenyuk, E.R., Kochetkov, S.N., Erokhin, V.V., Smirnova, T.G., Andreevskaia, S.N., Chernousova, L.N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: A.I. Gordeyev 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347540/
https://ncbi.nlm.nih.gov/pubmed/22649636
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