High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors

High-risk human papillomavirus type 16 (HPV16) is the primary causative agent of cervical cancer and therefore is responsible for significant morbidity and mortality worldwide. Cellular transformation is mediated directly by the expression of viral oncogenes, the least characterized of which, E5, su...

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Detalhes bibliográficos
Main Authors: Wetherill, Laura F., Holmes, Kristopher K., Verow, Mark, Müller, Marietta, Howell, Gareth, Harris, Mark, Fishwick, Colin, Stonehouse, Nicola, Foster, Richard, Blair, G. Eric, Griffin, Stephen, Macdonald, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347351/
https://ncbi.nlm.nih.gov/pubmed/22357280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06243-11
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