Virus Inhibition Activity of Effector Memory CD8(+) T Cells Determines Simian Immunodeficiency Virus Load in Vaccinated Monkeys after Vaccine Breakthrough Infection

The goal of an effective AIDS vaccine is to generate immunity that will prevent human immunodeficiency virus 1 (HIV-1) acquisition. Despite limited progress toward this goal, renewed optimism has followed the recent success of the RV144 vaccine trial in Thailand. However, the lack of complete protec...

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Detalhes bibliográficos
Main Authors: Yamamoto, Takuya, Johnson, Matthew J., Price, David A., Wolinsky, David I., Almeida, Jorge R., Petrovas, Constantinos, Nason, Martha, Yeh, Wendy W., Shen, Ling, Roederer, Mario, Rao, Srinivas S., McDermott, Adrian B., Lefebvre, Francois, Nabel, Gary J., Haddad, Elias K., Letvin, Norman L., Douek, Daniel C., Koup, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347297/
https://ncbi.nlm.nih.gov/pubmed/22419810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00315-12
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