Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Replication by Targeting the Interaction between Vif and ElonginC

The HIV-1 viral infectivity factor (Vif) protein is essential for viral replication. Vif recruits cellular ElonginB/C-Cullin5 E3 ubiquitin ligase to target the host antiviral protein APOBEC3G (A3G) for proteasomal degradation. In the absence of Vif, A3G is packaged into budding HIV-1 virions and int...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Zuo, Tao, Liu, Donglai, Lv, Wei, Wang, Xiaodan, Wang, Jiawen, Lv, Mingyu, Huang, Wenlin, Wu, Jiaxin, Zhang, Haihong, Jin, Hongwei, Zhang, Liangren, Kong, Wei, Yu, Xianghui
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347289/
https://ncbi.nlm.nih.gov/pubmed/22379088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06957-11
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍