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Joining of nonhomologous DNA double strand breaks in vitro.
Extracts of Xenopus laevis eggs can efficiently join ends of duplex DNA that differ in structure and sequence. This was analysed by recircularisation of linear plasmid DNA molecules with dissimilar termini, generated by successive cuts with two different restriction enzymes within the pSP65 polylink...
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| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1988
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334727/ https://ncbi.nlm.nih.gov/pubmed/3344222 |
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