SUMO Binding by the Epstein-Barr Virus Protein Kinase BGLF4 Is Crucial for BGLF4 Function

An Epstein-Barr virus (EBV) protein microarray was used to screen for proteins binding noncovalently to the small ubiquitin-like modifier SUMO2. Among the 11 SUMO binding proteins identified was the conserved protein kinase BGLF4. The mutation of potential SUMO interaction motifs (SIMs) in BGLF4 ide...

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Main Authors: Li, Renfeng, Wang, Leyao, Liao, Gangling, Guzzo, Catherine M., Matunis, Michael J., Zhu, Heng, Hayward, S. Diane
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347263/
https://ncbi.nlm.nih.gov/pubmed/22398289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00314-12
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