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Alternative Splicing within the elk-1 5′ Untranslated Region Serves To Modulate Initiation Events Downstream of the Highly Conserved Upstream Open Reading Frame 2

The 5′ untranslated region (UTR) plays a central role in the regulation of mammalian translation initiation. Key components include RNA structure, upstream AUGs (uAUGs), upstream open reading frames (uORFs), and internal ribosome entry site elements that can interact to modulate the readout. We prev...

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Detalhes bibliográficos
Main Authors: Rahim, Gwendoline, Araud, Tanguy, Jaquier-Gubler, Pascale, Curran, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347237/
https://ncbi.nlm.nih.gov/pubmed/22354998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06751-11
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