Development and Evaluation of a Novel Pellet-Based Tablet System for Potential Colon Delivery of Budesonide

Budesonide, a potent glucocorticoid, is used for the treatment of inflammatory bowel diseases. Current available oral formulations of budesonide have low efficacy against ulcerative colitis because of the premature drug release in the upper part of the gastrointestinal tract. In this paper a pH- and...

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Hlavní autoři: Varshosaz, Jaleh, Emami, Jaber, Tavakoli, Naser, Minaiyan, Mohsen, Rahmani, Nakisa, Dorkoosh, Farid
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346988/
https://ncbi.nlm.nih.gov/pubmed/22577558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/905191
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