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Prenatal Exposure to Polycyclic Aromatic Hydrocarbons, Benzo[a]pyrene–DNA Adducts, and Genomic DNA Methylation in Cord Blood

Background: Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic environmental pollutants generated during incomplete combustion. After exposure and during metabolism, PAHs can form reactive epoxides that can covalently bind to DNA. These PAH–DNA adducts are established markers of cancer risk. P...

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Bibliographic Details
Main Authors: Herbstman, Julie B., Tang, Deliang, Zhu, Deguang, Qu, Lirong, Sjödin, Andreas, Li, Zheng, Camann, David, Perera, Frederica P.
Format: Artigo
Language:Inglês
Published: National Institute of Environmental Health Sciences 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346775/
https://ncbi.nlm.nih.gov/pubmed/22256332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1104056
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