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Learning Transcriptional Regulatory Relationships Using Sparse Graphical Models

Understanding the organization and function of transcriptional regulatory networks by analyzing high-throughput gene expression profiles is a key problem in computational biology. The challenges in this work are 1) the lack of complete knowledge of the regulatory relationship between the regulators...

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Autors principals: Zhang, Xiang, Cheng, Wei, Listgarten, Jennifer, Kadie, Carl, Huang, Shunping, Wang, Wei, Heckerman, David
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346750/
https://ncbi.nlm.nih.gov/pubmed/22586449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035762
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