Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines

BACKGROUND: To improve cancer therapy, it is critical to target metastasizing cells. Circulating tumor cells (CTCs) are rare cells found in the blood of patients with solid tumors and may play a key role in cancer dissemination. Uncovering CTC phenotypes offers a potential avenue to inform treatment...

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Detalhes bibliográficos
Main Authors: Powell, Ashley A., Talasaz, AmirAli H., Zhang, Haiyu, Coram, Marc A., Reddy, Anupama, Deng, Glenn, Telli, Melinda L., Advani, Ranjana H., Carlson, Robert W., Mollick, Joseph A., Sheth, Shruti, Kurian, Allison W., Ford, James M., Stockdale, Frank E., Quake, Stephen R., Pease, R. Fabian, Mindrinos, Michael N., Bhanot, Gyan, Dairkee, Shanaz H., Davis, Ronald W., Jeffrey, Stefanie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346739/
https://ncbi.nlm.nih.gov/pubmed/22586443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033788
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