γ sulphate PNA (PNA S): Highly Selective DNA Binding Molecule Showing Promising Antigene Activity

Peptide Nucleic Acids (PNAs), nucleic acid analogues showing high stability to enzyme degradation and strong affinity and specificity of binding toward DNA and RNA are widely investigated as tools to interfere in gene expression. Several studies have been focused on PNA analogues with modifications...

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Detalhes bibliográficos
Main Authors: Avitabile, Concetta, Moggio, Loredana, Malgieri, Gaetano, Capasso, Domenica, Di Gaetano, Sonia, Saviano, Michele, Pedone, Carlo, Romanelli, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346730/
https://ncbi.nlm.nih.gov/pubmed/22586450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035774
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