Inhibition of Bacterial Biofilm Formation and Swarming Motility by a Small Synthetic Cationic Peptide

Biofilms cause up to 80% of infections and are difficult to treat due to their substantial multidrug resistance compared to their planktonic counterparts. Based on the observation that human peptide LL-37 is able to block biofilm formation at concentrations below its MIC, we screened for small pepti...

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Autors principals: de la Fuente-Núñez, César, Korolik, Victoria, Bains, Manjeet, Nguyen, Uyen, Breidenstein, Elena B. M., Horsman, Shawn, Lewenza, Shawn, Burrows, Lori, Hancock, Robert E. W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346644/
https://ncbi.nlm.nih.gov/pubmed/22354291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00064-12
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