No Effect of a Single Supratherapeutic Dose of Lersivirine, a Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor, on Corrected QT Interval in Healthy Subjects

The objective of this study was to investigate the effect of a supratherapeutic dose of lersivirine (LRV) on corrected QT (QTc) interval using Fridericia's equation (QTcF) in healthy subjects. In this randomized, single-dose, placebo- and active-controlled 3-way crossover study, healthy adult m...

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Hlavní autoři: Vourvahis, Manoli, Wang, Rong, Ndongo, Marie-Noella, O'Gorman, Melissa, Tawadrous, Margaret
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Clinical Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346613/
https://ncbi.nlm.nih.gov/pubmed/22371898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05194-11
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