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Comparative In Vivo Efficacies of Epithelial Lining Fluid Exposures of Tedizolid, Linezolid, and Vancomycin for Methicillin-Resistant Staphylococcus aureus in a Mouse Pneumonia Model

The antibacterial efficacies of tedizolid phosphate (TZD), linezolid, and vancomycin regimens simulating human exposures at the infection site against methicillin-resistant Staphylococcus aureus (MRSA) were compared in an in vivo mouse pneumonia model. Immunocompetent BALB/c mice were orally inocula...

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Main Authors: Tessier, Pamela R., Keel, Rebecca A., Hagihara, Mao, Crandon, Jared L., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346598/
https://ncbi.nlm.nih.gov/pubmed/22354302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06427-11
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