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Efflux Pumps of Mycobacterium tuberculosis Play a Significant Role in Antituberculosis Activity of Potential Drug Candidates

Active efflux of drugs mediated by efflux pumps that confer drug resistance is one of the mechanisms developed by bacteria to counter the adverse effects of antibiotics and chemicals. To understand these efflux mechanisms in Mycobacterium tuberculosis, we generated knockout (KO) mutants of four effl...

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Detalhes bibliográficos
Main Authors: Balganesh, Meenakshi, Dinesh, Neela, Sharma, Sreevalli, Kuruppath, Sanjana, Nair, Anju V., Sharma, Umender
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346595/
https://ncbi.nlm.nih.gov/pubmed/22314527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06003-11
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